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WP5 - Electronically programmable chemical matrix

WP5 has a significant integration character and is central to the establishment of a programmable generator for various labeled containers using microfluidics to build up a molecular container-post-system. We proposed an integrated microsystem for a programmable matrix for iterative processing of informational molecules via a delivery of container contents involving a fast serial communication as well as slow hydrogel gel based reaction processing tracks. First microfluidic systems have been designed and are now in the construction process.

The experimental platform (Chemical microprocessor) in MATCHIT is based on a hybrid microfluidic chip containing a silicon substrate with integrated gold electrodes and a micromoulded fluidic layer, which consists of a network a railway-like branching network of equally spaced electrodes, arranged in 48 blocks containing 82 individual controlled electrodes for cyclic molecular processing. Changing to a multilayer electronic chip design, the integration density could be increased to more than 5.000 electrodes for the same chip space, which allows a high application potential for creating intelligent microfluidics in the MATCHIT project, e.g electronic programmable separations and repackaging of container contents.

During the first eight months of the project, we have made significant progress on the experimental front regarding external Chemtainer droplet generation using ionic liquids. Together with our experimental partners from SDU we are involved in ongoing activities to test interactions at the phase interface of ionic liquids (as a potential carrier fluid to produce droplets in microchannels) with vesicles, oildroplets as well as the reverse micelles and DNA-based nanocontainers.